Current Projects
-
"SysTryp: Metabolomic systems biology analysis
of
differentiation in trypanosomes"
Mike
Barrett and
Fabien Jourdan (PIs), 3 others (including myself) and 7
partners. Funding from BBSRC and ANR (France), January 2008, 3 years.
-
"Glasgow iGEM",
international Genetically engineered Machines
Competition,
David Gilbert and
Susan Rosser (PIs).
Funding from the European Union and Scottish Enterprise.
July-November 2007.
-
"The Molecular Nose"
EPSRC, June 2007, 4 years
University of Glasgow:
Walter Kolch (PI) (Beatson Institute for Cancer Research),
Andy Pitt (Molecular and Cell Biology),
Jon Cooper (Bionanotechnology and Microfluidics),
Muffy Calder (Computing Science),
David Gilbert (Computing Science),
Mark Girolami (Bioinformatics and Computational Science).
University of Strathclyde:
Duncan Graham (Pure and Applied Chemistry),
Karen Faulds (Raman Spectroscopy).
MRC Genetics Unit:
Howard Cooke (Molecular Biology and mouse models) (Edinburgh).
-
"SIMAP: Simulation modelling of the MAP kinase
pathway",
David Gilbert (PI),
European Union FP6, January 2006, 3 years (Consortium of 9 members, led by
Compugen, Israel).
-
Stochastic Modelling and Statistical Inference of Gene Regulatory Pathways:
Integrating Multiple Sources of Data,
Ernst Wit (PI),
Mark Girolami
and
Walter Kolch.
EPSRC, September 2005, 3 years.
-
"Scottish
Bioinformatics Research Network (SBRN)"
Comprising the Universities of Dundee (lead institution), Edinburgh and Glasgow, the Scottish
Crop Research Institute (SCRI), Biomathematics and Statistics Scotland (BIOSS)
and the Scottish Bioinformatics Forum.
Funding from the Scottish Higher Education Funding Council (SHEFC), the Scottish Executive
Environment and Rural Affairs Department (SEERAD), and Scottish Enterprise
for four years from October 2004.
-
"Biochemical
Network Data Mined from Scientific Texts"
Bioinformatics Research Centre, University of Glasgow and
MD Biosciences.
Tamara Polajnar
(PhD student),
David Gilbert (PI),
Iadh Ounis,
Paul Garside (MD Biosciences).
PhD Industrial Studentship, funded by
Scottish Enterprise through
their
Life
Sciences
programme,
36 months from November 2005.
-
"Cardiovascular Functional Genomics"
Anna Dominiczak
(BHF Blood Pressure Group,
Medicine and Theraputics),
David Gilbert,
Ela Hunt (collaborator),
funded by the Wellcome Trust,
collaboration between 5 large research groupings in the UK,
5 years from August 2002.
-
David Gilbert's PhD students
-
Pawel Herzyk's PhD students:
-
David Cook
Towards genome-wide prediction of three-dimensional structure of transmembrane domains
in integral membrane proteins from sequence data
-
Ela Hunt:
-
Susan Fairley, MRC PhD studentship.
Database techniques for hypertension gene finding and analysis. Collaboration
with Prof Anna Dominiczak, Medicine.
-
Joanna Jakubowska,
MRC PhD studentship. "Visualization for e-Science and functional
genomics".
Past projects
-
"Modelling, Inference and Analysis for Biological Systems up to the
Cellular Level",
BBSRC Research Equipment Grant
(David Gilbert, PI),
December 2005.
-
"Targetted Manipulation of Signal Transduction Pathways based on In Silico
Modelling"
Faculty of Biomedical and Life Sciences, University of Glasgow and
Cyclacel.
Amelie Gourmand (PhD student),
Walter Kolch (PI).
PhD Industrial Studentship, funded by
Scottish Enterprise through
their
Biotechnology programme,
36 months from January 2004.
-
SB(R)Net -- Systems Biology Regional
Network.
Partner institutions:
University of Ulster (Co-ordinator),
University of Liverpool,
University of Wales -- Aberystwyth,
University of Wales -- Bangor,
Queen's University Belfast,
University College Dublin,
University of Glasgow.
-
"BPS: A Software Tool for the Simulation and Analysis of Biochemical
Networks"
David Gilbert (PI),
Muffy Calder,
Walter Kolch,
Keith van Rijsbergen:
Funding is for 4 years
provided by the
Department of Trade and Industry UK, under
the Beacon scheme.
Partners:
Bioinformatics Research Centre -
Department
of Computing Science and the Beatson Institute,
University of Glasgow. The industrial
partner is MD Biosciences.
Project presentation slideshow: HTML,
PDF
-
"Graph based methods for the analysis of biochemical structures"
Juris Viksna,
EPSRC Visiting Research Fellow,
(David Gilbert, PI),
April 2005 for 1 year
-
Prof Des Higham and
David Gilbert's PhD students
-
"Disease Prediction, Differentiation and Biomarker Identification from
Proteomic Profiling"
funded by
Mosaiques Diagnostics & Therapeutics AG.
Mark Girolami
-
"Probalistic reconstruction of signalling pathways and identification of novel
transcription factors",
Mark Girolami,
MRC discipline hopping
award,
April 2005, 8 months.
-
"BRIDGES: BioMedical
Research Informatics Delivered by Grid Enabled Services"
EPSRC, UK e-Science Core Programme project, 23 months.
David Gilbert (P.I.),
Malcolm Atkinson (P.I.),
Richard Sinnott (Project
manager), and
Ela Hunt.
-
"Inter-residue Interactions in Protein Structures"
Bioinformatics Research Centre, University of Glasgow and the
Computational Biology Research Center,
Tokyo, Japan.
David Gilbert (PI),
Pawel Herzyk,
Makiko Suwa
and
Michael Gromiha,
funded by the DAIWA
Anglo-Japanese Foundation,
12 months from 30 October 2003
-
"XTECT project (Xml TEchnologies for the discovery of Cancer
Treatments)"
Ela Hunt, P.I., in collaboration with J. Wilson of Strathclyde University and
B. Gusterson and Torsten Stein of the Division of Cancer Sciences and
Molecular Pathology, University of Glasgow.
Funded by the Carnegie Trust for the Univeristies of Scotland and the
Synergy Initiative.
-
Large scale data integration and the use of cross-genome mapping methods in
heart disease genetics and therapy
MRC Special Research Training
Fellowship in Bioinformatics, Ela Hunt (PI), 4 years from 1 October
2001.
-
Mallika Veeramalai,
,
PhD student,
"Incorporating sequence and interaction information in topological models of
protein structure". October 2001 - September 2005
-
Ali Al-Shahib,
,
PhD student
"Assigning function to genes using a
variety of data sources by combining predications with varying levels of
uncertainty"
. October 2001 - June 2005
-
"Representation and
Exploitation of Diverse Biological Evidence in a Systems Biology
Context"
Rainer Breitling:
Personal Research Fellowship funded by the Caledonian
Research Foundation. April 2005.
-
"Automatic extraction
of rules for protein classification"
Juris Viksna:
funded by the Wellcome Trust, and the University of
Glasgow.
-
"Functional
Genomics of NutriensTransport in Arabidopsis; Bioinformatics
Approach"
Anna
Amtmann,
Pawel Herzyk,
Ernst Wit and
Rainer Breitling
BBSRC, April 2003
for 2 years
-
"
Patterns, functions and structures on a protein topology database"
initially
funded by the BBSRC/EPSRC Bioinformatics Initiative, 2 years from January
2001, thereafter funded by the University of Glasgow for 2 years.
David Gilbert (PI) and
Gilleain Torrance.
Rated A ("Very high class work that has produce results of considerable
scientific importance")
-
Andrew Jones, MRC PhD studentship:
Database technologies for large proteomics data sets. Collaboration with
Dr Jonathan Wastling, IBLS.
-
Aik Choon Tan, PhD student,
"Machine learning of protein
structure and function"
-
"Engineering Cell Form and Function with Nanometric Surfaces"
Mathis
Riehle, David Gilbert,
Chris Wilkinson and
Stephen Yarwood,
a collaboration between the
Centre for Cell Engineering
and the
Bioinformatics Research Centre.
Funded by the
Royal Society Wolfson Foundation Laboratory Refurbishment Scheme,
February 2003 for 1 year
-
"SAILS: Self-Adjusting Indexes for Large Sequences"
Malcolm Atkinson (PI) and
Nigel Harding.
Funded by the EPSRC, 30
months from August 2001.
-
"Application of constraint satisfaction for the analysis of
biochemical networks"
Yves Deville and
David Gilbert,
September 2002 for 1 year, funded by the
EPSRC
-
"Structural patterns in the composite regulatory regions of
genomes"
Olivier Sand:
Funded by a Marie Curie Research Fellowship, and the University of
Glasgow.